What are your favorite perks to combine on a single person? How do they work out for you? Do you have any real "go-to" combinations?
My favorite right now is Oblivious with Shield of Hope. The constant boost of morale makes the survivor difficult to kill, and I've needed Shield of Hope to activate more times than I'd like to admit... So that was pretty nice. The additional perks of an Oblivious personality also make the character handy in text-based events, of course.
I also love having the Surgeon and Nurturing combo as a designated medic character, but I will also use Healthcare + Hero Type as a sort of auxillary medic that has the supplies and can save your allies from death.
Pathfinder with City Seeker makes a great navigator and has a decent chance of netting a lot of good loot throughout the trip.